Cart
sales@molnova.com
SB269970 HCl
CAS No. 261901-57-9
SB269970 HCl( SB-269970A )
Catalog No. M17459 CAS No. 261901-57-9
SB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 45 | In Stock |
|
| 5MG | 61 | In Stock |
|
| 10MG | 113 | In Stock |
|
| 25MG | 243 | In Stock |
|
| 50MG | 426 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSB269970 HCl
-
NoteResearch use only, not for human use.
-
Brief DescriptionSB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
-
DescriptionSB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
-
In Vitro——
-
In VivoSB269970 hydrochloride (SB-269970A) (3-30 mg/kg; i.p.; once) significantly blocks amphetamine and ketamine-induced hyperactivity. Animal Model:Male C57BL6/J miceDosage:3, 10, 30 mg/kg Administration:Intraperitoneal injection; onceResult:Significantly blocked amphetamine and ketamine-induced hyperactivity.
-
SynonymsSB-269970A
-
PathwayMembrane Transporter/Ion Channel
-
TargetTRP/TRPV Channel
-
Recptor5-HT7
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number261901-57-9
-
Formula Weight388.95
-
Molecular FormulaC18H28N2O3S·HCl
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 30 mg/mL; 77.13 mM
-
SMILESCl.CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hagan JJ, et al. Br J Pharmacol, 2000, 130(3), 539-548.
molnova catalog
related products
-
RN9893
RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.
-
Palvanil
Palvanil is a fast desensitizing agonist of TRPV1. it may be promising agents in the therapy of IBS since it modulates intestinal motility and reduces visceral pain.
-
AMG-333
AMG-333 (AMG333, AMG 333) is a novel potent, highly selective TRPM8 antagonist with IC50 of 13 nM and 20 nM for hTRPM8 and rTRPM8, respectively.
